adaptyv

---
name: adaptyv
description: Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.
---

# Adaptyv

Adaptyv is a cloud laboratory platform that provides automated protein testing and validation services. Submit protein sequences via API or web interface and receive experimental results in approximately 21 days.

## Quick Start

### Authentication Setup

Adaptyv requires API authentication. Set up your credentials:

1. Contact support@adaptyvbio.com to request API access (platform is in alpha/beta)
2. Receive your API access token
3. Set environment variable:

```bash
export ADAPTYV_API_KEY="your_api_key_here"
```

Or create a `.env` file:

```
ADAPTYV_API_KEY=your_api_key_here
```

### Installation

Install the required package using uv:

```bash
uv pip install requests python-dotenv
```

### Basic Usage

Submit protein sequences for testing:

```python
import os
import requests
from dotenv import load_dotenv

load_dotenv()

api_key = os.getenv("ADAPTYV_API_KEY")
base_url = "https://kq5jp7qj7wdqklhsxmovkzn4l40obksv.lambda-url.eu-central-1.on.aws"

headers = {
    "Authorization": f"Bearer {api_key}",
    "Content-Type": "application/json"
}

# Submit experiment
response = requests.post(
    f"{base_url}/experiments",
    headers=headers,
    json={
        "sequences": ">protein1\nMKVLWALLGLLGAA...",
        "experiment_type": "binding",
        "webhook_url": "https://your-webhook.com/callback"
    }
)

experiment_id = response.json()["experiment_id"]
```

## Available Experiment Types

Adaptyv supports multiple assay types:

- **Binding assays** - Test protein-target interactions using biolayer interferometry
- **Expression testing** - Measure protein expression levels
- **Thermostability** - Characterize protein thermal stability
- **Enzyme activity** - Assess enzymatic function

See `reference/experiments.md` for detailed information on each experiment type and workflows.

## Protein Sequence Optimization

Before submitting sequences, optimize them for better expression and stability:

**Common issues to address:**
- Unpaired cysteines that create unwanted disulfides
- E

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